NFL Week 12 Expert Tips & Predictions

The NFL continues with Week 12 action, and we have NFL expert betting picks and predictions for every game of the year.

It starts with the Bills vs. Texans on Friday, and the featured games this week include Vikings vs. Packers, Colts vs. Chiefs, and Buccaneers vs. Rams.

NFL Week 12 Predictions

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Friday 21/11/25

12:15pm Bills vs. Texans @ NRG Stadium

Betting Tip: Bills –5.5 @ $1.90

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The Bills got back to their best last week with a comfortable win, and they have enough firepower to handle the Texans on the road.

We’re surprised to see the line only at –5.5, as we rated the Bills at –7.5. Josh Allen has his confidence levels back up, which could be enough to see the Bills score by double digits.

Include them in your NFL multi bets this week.

Bills by 10

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Monday 24/11/25

5:00am Steelers vs Bears @ Soldier Field

Betting Tip: Bears -2.5 @ $1.90

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The Bears are going under the radar this season, and with Aarno Rodgers suffering an injury for the Steelers, they’ll likely be without their star QB.

It’s not always easy to trust the Bears, but they are 7-3 after a slow start to the year, and they should continue to build that record.

The –2.5 line is another generous offering from bookmakers.

Bears by 7

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5:00am Patriots vs. Bengals @ Paycor Stadium

Betting Tip: Patriots –7.5 @ $1.90

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The Patriots have been the surprise package of the season. They are 9-2 and 5-0 on the road, which shows how much they have grown over the last few years since Tom Brady and Bill Belichick left town.

It’s a new era for the Patriots, and they should be far too good for the struggling Bengals. Not much has gone right for the Bengals, who lost Joe Burrow early on.

Covering a 7.5-point spread isn’t easy, but class should shine through.

Patriots by 10

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5:00am Giants vs. Lions @ Ford Field

Betting Tip: Lions –10.5 @ $1.90

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More is needed from the Lions after losing to the Philadelphia Eagles on Tuesday, but this should be a much easier task this week.

The Giants’ season has been imploded by injuries, and they are 0-6 on the road, which we can’t see improving anytime soon. They showed good fight early on, but they might have given up on anything happening this year.

Take the Lions to exert their class and win easily.

Lions by 14

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5:00am Vikings vs. Packers @ Lambeau Field

Betting Tip: Packers -6.5 @ $1.90

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This is a statement game for the Packers, who could win the rivalry clash. They are 6-3-1, and although they haven’t been at their brilliant best, they are better than the Vikings.

We haven’t been overly impressed by the 4-6 Vikings. They haven’t had a standout win, and Jordan Love could light up their defence.

Take the –6.5 line before money comes for the home team on game day.

Packers by 7

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5:00am Seahawks vs. Titans @ Nissan Stadium

Betting Tip: Seahawks –13.5 @ $1.90

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The Seahawks need to play well to cover the –13.5 spread, but the Titans are in give up mode after winning just one game.

There is nothing going right for the Titans, who are looking to secure a top draft pick, and that’s why we’re not including them in our NFL picks this week.

It’s not our most confident bet of the week, but include the Seahawks in NFL multis.

Seahawks by 14

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5:00am Colts vs. Chiefs @ GEHA Field

Betting Tip: Colts @ $2.50

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There is good value with the Colts at $2.50. They are well-rested, and the Chiefs come off a tough loss to the Denver Broncos.

The Colts have a strong Super Bowl chance at 8-2, and they have a good QB and running back, coupled with a tough defence. That’s enough to include them in picks against the Chiefs, who haven’t been at their best this season.

We’re backing the better team at a better price.

Colts by 6

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5:00am Jets vs. Ravens @ M&T Bank Stadium

Betting Tip: Ravens –13.5 @ $1.90

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It has been a good job from the Ravens just to get back to .500, and they’re seeking a playoff spot.

They were the Super Bowl favourites with pre-season betting markets, but they made a terrible start to the year. However, they’re riding a winning streak with Lamar Jackson back in the team after suffering an injury.

The Jets are distinctly terrible, so take the line with the Ravens.

Ravens by 20

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8:05am Browns vs. Raiders @ Allegiant Stadium

Betting Tip: Browns @ $2.47

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The Browns and Raiders are 2-8, so there isn’t much going right for them. Shedeur Sanders got a reality check last week, but with that experience under his belt, he could come with a better game plan.

The Ravens rushed him at every chance they got, and it worked. However, the Raiders’ defence isn’t as good, and he could have some success.

We’re happy to take the risk by backing the Browns at underdog odds.

Browns by 3

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8:05am Jaguars vs. Cardinals @ State Farm Stadium

Betting Tip: Jaguars -2.5 @ $1.90

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There isn’t much consistency with the Jaguars, but they were good last week, and we’re hoping that form comes to the table.

We haven’t been impressed by the Cardinals, who are only 1-4 at home, and that’s not good enough for us to recommend backing them.

Take the Jags –2.5, which is a good line.

Jaguars by 7

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8:25am Eagles vs. Cowboys @ AT&T Stadium

Betting Tip: Eagles -3.5 @ $1.90

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The Eagles’ defence is one of the best in the NFL, and they showed that when beating the Lions last week. That was a tough effort, and it was needed because the offence isn’t firing on all cylinders.

We expect more from Jalen Hurts and Saquon Barkley, who have been disappointing in recent weeks. However, the Cowboys aren’t a good football team, and they’re there for the taking in Week 12.

We’re jumping on the –3.5 line for the Super Bowl champions.

Eagles by 7

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8:25am Falcons vs. Saints @ Caesars Superdome

Betting Tip: Saints @ $1.79

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The Saints are only 2-8, and they’re not our best bet of the week, but they are good enough to beat the Falcons.

Spencer Rattler is suffering some growing pains, but he has eight touchdowns and five interceptions, and his numbers should improve with time.

A field goal could be all that splits this team.

Saints by 3

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12:30pm Buccaneers vs. Rams @ SoFi Stadium

Betting Tip: Rams -6.5 @ $1.90

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The Rams are sneaking under the radar in Super Bowl markets despite being 8-2. They are playing excellent football, and they’re led by Matthew Stafford.

The MVP candidate has 27 touchdowns and only two interceptions, which are great numbers. It has been a resurgent year for the seasoned pro, and he could keep throwing at an elite level against the Buccaneers.

It will be an offence-heavy game, where the Rams should prevail.

Rams by 10

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Tuesday 18/11/25

12:15pm Panthers vs. 49ers @ Levi’s Stadium

Betting Tip: Panthers +6.5 @ $1.90

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It should be a close game between the Panthers and 49ers, so we’re taking the Panthers with a +6.5 line.

Most of the money has come for the 49ers to cover the spread at home, but the Panthers’ defence is good enough to keep them in the game.

Mac Jones’ stock has gone down over the last few weeks, so an upset could happen here.

49ers by 3

Editor In Chief

Daryl Curnow

After graduating from the University of Auckland (BA - English), Daryl was thrown into the world of sports and horse racing journalism.

Having worked as a racing journalist for two years, he decided to move into the online world of horse racing and sports writing. After years of honing his craft, Daryl became a professional punter in 2009 - with a focus on horse racing, NRL, AFL, NBA, Rugby, NFL, and US college sports.

Daryl's tips have been featured on various websites around the world before joining the GoBet team. When he's not working, Daryl tries to avoid making bogeys on the golf course.